PhD positions: brain & cardiovascular development

BCN-Medtech, Universitat Pompeu Fabra
Location: 
Barcelona
Job Type: 
Full Time
Closing Date: 
Monday, July 23, 2018

<p style="margin:0cm 0cm 0.0001pt; -webkit-text-stroke-width:0px; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><font face="arial, helvetica, sans-serif"><b><span style="font-size:small; text-align:justify"><span style="color:#222222"><span style="font-family:arial, helvetica, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="letter-spacing:normal"><span style="text-transform:none"><span style="white-space:normal"><span style="word-spacing:0px"><span style="background-color:#ffffff"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="float:none"><span style="display:inline">Workplace</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></b></font></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; -webkit-text-stroke-width:0px; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><font face="arial, helvetica, sans-serif"><b><span style="font-size:small; text-align:justify"><span style="color:#222222"><span style="font-family:arial, helvetica, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="text-transform:none"><span style="white-space:normal"><span style="word-spacing:0px"><span style="background-color:#ffffff"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="float:none"><span style="display:inline">The projects will be conducted&nbsp;</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span><i style="color:#222222; font-family:arial, helvetica, sans-serif; font-size:small; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; text-align:justify; text-transform:none; white-space:normal; word-spacing:0px; background-color:#ffffff; text-decoration-style:initial; text-decoration-color:initial">at the Universitat Pompeu Fabra, Barcelona, Spain,&nbsp;</i><span style="font-size:small; text-align:justify"><span style="color:#222222"><span style="font-family:arial, helvetica, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="text-transform:none"><span style="white-space:normal"><span style="word-spacing:0px"><span style="background-color:#ffffff"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="float:none"><span style="display:inline">for the computational part (supervised by ICREA Research Prof. B. Bijnens and Dr. Oscar Camara)</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span><i style="color:#222222; font-family:arial, helvetica, sans-serif; font-size:small; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; text-align:justify; text-transform:none; white-space:normal; word-spacing:0px; background-color:#ffffff; text-decoration-style:initial; text-decoration-color:initial">&nbsp;</i><span style="font-size:small; text-align:justify"><span style="color:#222222"><span style="font-family:arial, helvetica, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="text-transform:none"><span style="white-space:normal"><span style="word-spacing:0px"><span style="background-color:#ffffff"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="float:none"><span style="display:inline">and in the&nbsp;</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span><i style="color:#222222; font-family:arial, helvetica, sans-serif; font-size:small; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; text-align:justify; text-transform:none; white-space:normal; word-spacing:0px; background-color:#ffffff; text-decoration-style:initial; text-decoration-color:initial">Fetal Medicine Research Centre,</i><span style="font-size:small; text-align:justify"><span style="color:#222222"><span style="font-family:arial, helvetica, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="text-transform:none"><span style="white-space:normal"><span style="word-spacing:0px"><span style="background-color:#ffffff"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="float:none"><span style="display:inline">&nbsp;at the&nbsp;</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span><i style="color:#222222; font-family:arial, helvetica, sans-serif; font-size:small; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; text-align:justify; text-transform:none; white-space:normal; word-spacing:0px; background-color:#ffffff; text-decoration-style:initial; text-decoration-color:initial">Maternity Hospital of Hospital Clínic&nbsp;</i><span style="font-size:small; text-align:justify"><span style="color:#222222"><span style="font-family:arial, helvetica, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="text-transform:none"><span style="white-space:normal"><span style="word-spacing:0px"><span style="background-color:#ffffff"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="float:none"><span style="display:inline">(supervised by Dr F. Crispi, Dr. E. Eixarch and Prof E. Gratacos). Other (international) collaborators will be involved, depending on the project.</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></b></font></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>

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<p style="margin:0cm 0cm 0.0001pt; -webkit-text-stroke-width:0px; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><font face="arial, helvetica, sans-serif"><b>PhD project 1:&nbsp;&nbsp;Development of a multi-scale model of the cardiovascular system of a foetus with aortic coarctation</b></font></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; -webkit-text-stroke-width:0px; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><span lang="EN-GB" style="font-family:Arial">The aim of this project is the development of a multi-scale model of the cardiovascular system of a fetus with aortic coarctation (and related defects such as ventricular or atrial septal defects), including also the implementation of a tissue growth model to be able to assess the cardiac growth and remodelling during development. It will consist on a 0D model of the circulation, including all the relevant vessels and vascular beds, potentially coupled to a simple 3D model of the fetal heart. Then, a simplified mathematical model of cardiac growth and remodelling will be incorporated in order to study the effects of hemodynamic and mechanical alterations under aortic coarctation into cardiac development.</span>&nbsp;</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>

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<p style="margin:0cm 0cm 0.0001pt; -webkit-text-stroke-width:0px; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><font face="arial, helvetica, sans-serif"><b>PhD project 2:&nbsp;&nbsp;&nbsp;<b>The Heart-Brain axis, or There and Back again: the journey towards brain development traverses vascular territories</b></b></font></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p><font face="arial, helvetica, sans-serif"><font style="color: rgb(34, 34, 34); font-size: 12.8px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-style: initial; text-decoration-color: initial; background-color: rgb(255, 255, 255);">The aim of this project is to create a computational modelling platform, linking heart and brain systems, to test the influence of mechanical forces originating from vascular anatomy, haemodynamics and metabolic characteristics on brain development in normal and abnormal conditions. This research will open up opportunities for understanding systems-based mechanisms of other conditions affecting heart and brain such as congenital heart disease, schizophrenia, autism, neurodegenerative diseases or neurocardiology applications.&nbsp;</font></font></p>

<div style="text-align:start; -webkit-text-stroke-width:0px"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><font face="arial, helvetica, sans-serif"><b>Profile of the candidates</b></font></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></div>

<div style="-webkit-text-stroke-width:0px; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><span lang="EN-GB" style="color:black; text-align:justify"><span style="font-family:arial, helvetica, sans-serif">We are looking for highly motivated young researchers with a Master degree (or equivalent) in Biomedical Engineering, Physics, Mechanical Engineering, Applied Mathematics, Computational Science, or related disciplines, willing to study and do research at the leading edge of biomedical engineering. Interest in biomedical and clinical applications is essential. Experience with computer sciences and having proven programming skills would be of importance.&nbsp;</span></span><span style="color:black; text-align:justify"><span style="font-family:arial, helvetica, sans-serif">Candidates must have excellent teamwork and communication skills and be enthusiastic about collaborating with a diverse range of international partners. We expect them to be fluent in English as this will be the language used to interrelate with the different partners.&nbsp;</span></span><span lang="EN-GB" style="text-align:justify; font-family:arial, helvetica, sans-serif">Female applicants are explicitly encouraged to apply and will be treated preferentially whenever they are equally qualified as other male candidates.</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></div>

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<p style="margin:0cm 0cm 0.0001pt; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><font face="arial, helvetica, sans-serif"><b>Practical information</b></font></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><span style="font-family:arial, helvetica, sans-serif">- Starting date: September 2018;&nbsp;</span><span style="font-size:12.8px; text-align:start">applicants will be reviewed on a continous basis and accepted until the positions are filled.&nbsp;</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; text-align:left"><span style="font-size:12.8px"><span style="color:#222222"><span style="font-family:arial, sans-serif"><span style="font-style:normal"><span style="font-variant-ligatures:normal"><span style="font-variant-caps:normal"><span style="font-weight:400"><span style="letter-spacing:normal"><span style="orphans:2"><span style="text-transform:none"><span style="white-space:normal"><span style="widows:2"><span style="word-spacing:0px"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="background-color:#ffffff"><font face="arial, helvetica, sans-serif">- Application: send a CV and a letter describing research interests to Bart Bijnens (<a href="mailto:bart.bijnens@upf.edu" style="color:#1155cc" target="_blank">bart.bijnens@upf.edu</a>) and Oscar Camara (<a href="mailto:oscar.camara@upf.edu" style="color:#1155cc" target="_blank">oscar.camara@upf.edu</a>)</font></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>
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